正文 原發性骨淋巴瘤誤診為腰椎間盤突出症1例(2 / 2)

總之,對病因未明的骨痛,在常規檢查下不能確診時,要考慮到腫瘤可能,盡早行骨組織活檢,以減少不良事件發生;影像學中骨質破壞形態和骨旁軟組織改變有助於骨淋巴瘤診斷,X線檢查對早期診斷存在局限性,CT、MRI對PBL的鑒別診斷及繼發性骨浸潤的識別判斷具有較高參考價值;患者即使有典型的下腰痛、附著點炎及放射學腰椎間盤局部炎性反應及神經受損等表現,即使符合腰椎間盤診斷標準,也要注意其他疾病的可能。值得臨床醫師重視。

[參考文獻]

[1] Hackshaw AK,Wald NJ. Assessement of the value of reporting partial screening results in prenatal screening for Down syndrome[J]. Prenat Diagn,2001,21(9):445-447.

[2] Nicolaides KH. Screening for chromosomal defects[J]. Ultrasound Obstet Gynecol,2003,21(4):313-321.

[3] Reddy N,Greer JP. Primary bone lymphoma: a set of unique problems in management[J]. Leuk Lymphoma,2010,51(1):1-2.

[4] 郭智,陳豐. 12例骨原發性淋巴瘤臨床分析[J]. 中華實用診斷與治療雜誌,2009,23(6):598-599.

[5] Ramadan KM,Shenkier T,Sehn LH,et al. A clinico-pathological retrospective study of 131 patients withprimary bone lymphoma: a population-based study ofsuccessively treated cohorts from the British Columbia Cancer Agency[J]. Ann Oncol,2007,18(1):129-135.

[6] 王書紅,於力,王全順,等. 骨原發非霍奇金淋巴瘤23例臨床分析[J]. 中國實驗血液學雜誌,2008,16(1):200-202.

[7] 朱海雲,王莉,田建明. 骨原發性淋巴瘤的MR表現[J]. 中國醫學影像技術,2004,20(11):1742-1744.

[8] Unni KK,Hogendoom PCW. World Health Organization classification of tumours pathology and genetics of tumours of soft tissue and bone[M]. Lyon:IARC Press,2002:194-198.

[9] 許尚文,成官迅,陳自謙,等. 骨原發性淋巴瘤的MRI表現[J]. 中國臨床醫學影像雜誌,2006,17(3):161-163.

(收稿日期:2013-01-17)